New Research Shows T-Line® Provides Earlier and More Reliable Detection of Hypotensive Events During Surgery

San Diego, CA | February 13, 2006 -- Research presented at the Society for Technology in Anesthesia.

Recent reports by Monk¹ and O'Reilly² showed an association between serious hypotension during surgery and increased 1-year postoperative mortality. Studies at the University of Colorado Health Science Center and the University of California at San Diego demonstrated that the Tensys® T-Line® non-invasive blood pressure monitor was more reliable in identifying sudden onset of serious hypotension during surgery than upper arm cuff blood pressure measurements (NIBP). Study findings were presented at the Society for Technology in Anesthesia annual meeting held in San Diego, CA. from January 18-21, 2006.

Twenty-five patients ranging from 49 to 83 years of age were enrolled and studied with automated upper arm cuff BP and contra-lateral T-Line® noninvasive beat-to-beat BP during general anesthesia for elective surgery. Serious hypotension was identified as systolic BP <85 mm Hg for >5 minutes. NIBP and contra-lateral noninvasive T-Line® BP were measured simultaneously during surgery. The attending anesthesiologist was blinded to the beat-to-beat T-Line® measurements and thus managed the case only with the NIBP cuff data.

Using a single patient use transducer, the T-Line® captures the radial artery and displays continuous BP information and a true arterial waveform. Data from this study showed that the T-Line® identified 18 episodes of systolic BP < 85 mm Hg while the cuff showed only 14 episodes, 4 of which were delayed. The mean delay was 3.6 minutes with a SD of 1.4.

Dr. Ron Dueck, Clinical Professor of Anesthesiology at UCSD concluded, "These findings indicate the T-Line® beat-to-beat BP monitor provides earlier, more reliable evidence of serious hemodynamic instability than conventional automated cuff BP. This enables early, effective therapy before it leads to significant morbidity."

Stuart Gallant, Chief Technical Officer at Tensys® Medical Inc, agreed with the interpretation."These data suggest that use of the T-Line® during routine surgery may enable more immediate and rapid intervention during hemodynamically significant episodes. With the T-Line®, we aim to provide the anesthesiologist another tool with which to safely manage hemodynamically unstable patients."

To view this abstract please click: www.tensysmedical.com/publications

About Tensys® Medical

Tensys® Medical, Inc. is the leader in real-time blood pressure management. The Tensys® T-Line®, the company's lead product, was cleared by the FDA in November 2002 for non-invasive, continuous real-time blood pressure monitoring.

The Tensys® T-Line® measures a patient's blood pressure at the radial artery. It offers anesthesiologists better, more effective control over patient safety during surgery by allowing them to quickly monitor and manage blood pressure variations. The T-Line® provides continuous, real-time data and has clinically equivalent accuracy to that of the arterial line (A-line). The device is based on Tensymetry®, the company's proprietary and patented technology for non-invasively extracting the continuous, beat-to-beat pressure waveform from the radial artery without the use of any external calibration device. The science of Tensymetry® is the result of over eight years of research and development

Tensys® Medical is based in San Diego, California and was founded in November 1995. For more information, please visit the company's Web site at www.tensysmedical.com.

Company Contacts:

Patti Duffy
Manager Customer Service
888.722.7800 ext.1
support@tensysmedical.com

References:

• Monk TG, Saini V, Weldon BC, Sigl JC. Anesthetic Management and One-Year Mortality after Noncardiac Surgery. Anesthesia & Analgesia 2005;100:4-10.
• O'Reilly M, Tremper KK, Shanks A, Kheterpal S, Campbell DA. Evaluating Surgical Outcomes Using the NSQIP database and Intraoperative Variables Using an Electronic Anesthesia Information System. American Society of Anesthesiologist 2005.